Historical Perspective of Arboviruses in Mozambique and Its Implication for Current and Future Epidemics.

In conclusion, the old literature on arboviruses in Mozambique is relevant for assessing the gaps and current risk of occurrence of these pathogens at the region, particularly in a time in which they are spreading worldwide. PMID: 29845522 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research

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This study defines grp94 as a crucial host factor for flavivirus replication and identified CDDO-me as a potent small molecule inhibitor of flavivirus infection. Inhibition of grp94 may contribute to the antiviral activity of CDDO-me. Further investigation of grp94 inhibitors may lead to a new class of broad-spectrum anti-flaviviral medications.
Source: Antiviral Therapy - Category: Virology Source Type: research
GIDEON what’s new summary: August 23 to August 25, 2019 Infectious Diseases – Outbreaks (17 updates) 17 DiseasesMap Infectious Diseases – Diseases (97 updates) 11 Clinical notes31 Diseases53 Country notes1 1 New Disease Synonym AddedMap Microbiology – Mycobacteria (1 updates) 1 Mycobacteria The post Update: August 25, 2019 appeared first on GIDEON - Global Infectious Diseases and Epidemiology Online Network.
Source: GIDEON blog - Category: Databases & Libraries Authors: Tags: What's New Source Type: blogs
Publication date: 24 August 2019Source: New Scientist, Volume 243, Issue 3244Author(s): Malaria is a distant problem for most of us. We shouldn't ignore it
Source: New Scientist - Category: Science Source Type: research
Authors: Abstract Zika virus is a flavivirus with the potential to cause serious adverse pregnancy and infant outcomes. Although rates of Zika virus infection have decreased in the United States, obstetrician-gynecologists and other health care providers should continue to assess their patients for potential exposure based on travel or sexual history and test symptomatic patients with possible exposure and pregnant women with ongoing exposure regardless of symptoms in accordance with the Centers for Disease Control and Prevention recommendations. Pregnant women and those planning a pregnancy should talk to their ...
Source: Obstetrics and Gynecology - Category: OBGYN Tags: Obstet Gynecol Source Type: research
Authors: Abstract Zika virus is a flavivirus with the potential to cause serious adverse pregnancy and infant outcomes. Although rates of Zika virus infection have decreased in the United States, obstetrician-gynecologists and other health care providers should continue to assess their patients for potential exposure based on travel or sexual history and test symptomatic patients with possible exposure and pregnant women with ongoing exposure regardless of symptoms in accordance with the Centers for Disease Control and Prevention recommendations. Pregnant women and those planning a pregnancy should talk to their ...
Source: Obstetrics and Gynecology - Category: OBGYN Tags: Obstet Gynecol Source Type: research
We present an unusual case of a large dumb-bell-shaped cold abscess arising due to infection of the sternum. A 23-year-old immunocompetent Asian woman presented with a gradually progressing painless swelling on anterior chest wall for the last 5  months. She had a large visible swelling on anterior chest wall which was 12.5 cm in diameter, soft, non-tender, temperature was not raised, and fluctuant. Magnetic resonance imaging showed a large dumb-bell-shaped hyperintense collection in upper anterior chest wall with marrow edema and corti cal irregularity in left side of manubrium. Pus was positive for nucleic ...
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Publication date: Available online 23 August 2019Source: Social Science &MedicineAuthor(s): Megan D. CogburnAbstractOver the last two decades, there has been a global push to improve maternal health by increasing numbers of facility births in low- and middle-income countries like Tanzania. While recent scholarship has interrogated the increasing hegemony of numbers and metrics in global health, few have ethnographically explored how this push for numbers and its accompanying technologies affect the lived experiences of parturients and those who care for them during pregnancy and childbirth in rural communities. Based o...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
In this study, we were able to demonstrate that our measure for mosquito-borne viral suitability is informative in the context of Myanmar, despite the lack of ento-epidemiological datasets with high spatio-temporal resolution. By estimating suitability through climate variables and known ento-epidemiological parameters, we were able to project mosquito-born virus (MBV) suitability at the district level, a resolution for which epidemiological data and mosquito abundance measures are not generally available. Here, we discuss the national and subnational public health and control implications for MBVs in the context of our pr...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
DAVID E. BLOOM is the Clarence James Gamble Professor of Economics and Demography, DANIEL CADARETTE is a research assistant, and JP SEVILLA is a research associate, all at Harvard University’s T.H. Chan School of Public Health.By David E. Bloom, Daniel Cadarette and JP SevillaWASHINGTON DC, Jul 3 2018 (IPS)Infectious diseases and associated mortality have abated, but they remain a significant threat throughout the world.We continue to fight both old pathogens, such as the plague, that have troubled humanity for millennia and new pathogens, such as human immunodeficiency virus (HIV), that have mutated or spilled over ...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Active Citizens Development & Aid Economy & Trade Global Headlines Health TerraViva United Nations Source Type: news
ConclusionsUsing a detailed agent-based dengue transmission model for Yucat án State, Mexico, we predict that high coverage indoor residual spraying (IRS) interventions can largely eliminate transmission for a few years, when applied a few months before the typical seasonal epidemic peak. However, vector control succeeds by preventing infections, which precludes natural im munization. Thus, as a population benefits from mosquito control, it gradually loses naturally acquired herd immunity, and the control effectiveness declines; this occurs across all of our modeled scenarios, and is consistent with other empirical ...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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