Justidrusamides A–D, new 2-aminobenzyl alcohol derivatives from Justicia gendarussa

Abstract Justidrusamides A–D (1–4), four new alkaloids containing 2-aminobenzyl alcohol, succinic acid, and 2,3-dihydroxy-2-(1-hydroxyethyl) butanoic acid skeletons have been isolated from leaves of Justicia gendarussa, and their structures were elucidated using 2D NMR data and chemical means. This is the first report of a 2,3-dihydroxy-2-(1-hydroxyethyl) butanoic acid derivative in nature.
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research