Polymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in Botswana

Polymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in BotswanaPolymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in Botswana, Published online: 01 June 2018; doi:10.1038/s41397-018-0028-2Polymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in Botswana

Source: The Pharmacogenomics Journal - June 1, 2018 Category: Drugs & Pharmacology Authors: Marijana Vujkovic Scarlett L. Bellamy Athena F. Zuppa Marc R. Gastonguay Ganesh S. Moorthy Bakgaki Ratshaa Xiaoyan Han Andrew P. Steenhoff Mosepele Mosepele Brian L. Strom Gregory P. Bisson Richard Aplenc Robert Gross Source Type: research