Age of onset of Cannabis use and cognitive function in first-episode non-affective psychosis patients: Outcome at three-year follow-up

In recent years, the effects of cannabis use on cognitive functions in patients with psychosis have been widely studied. Recently, special emphasis has been placed on the impact of age at the onset of consumption on cognition in these patients.
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research

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Publication date: Available online 24 April 2019Source: Journal of Psychiatric ResearchAuthor(s): Anastasia Hodes, Haim Rosen, Hagit Cohen-Ben Ami, David LichtsteinAbstractNa+, K+-ATPase is an essential membrane transporter. In the brain, the α3 isoform of Na+, K+-ATPase is vital for neuronal function. The enzyme and its regulators, endogenous cardiac steroids (ECS), were implicated in neuropsychiatric disorders. GABAergic neurotransmission was also studied extensively in diseases such as schizophrenia and bipolar disorder (BD). Post mortem brain samples from subjects with depression, schizophrenia or BD and non-psyc...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Publication date: Available online 24 April 2019Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Eric Vornholt, Dan Luo, Wenying Qiu, Gowon O. McMichael, Yangyang Liu, Nathan Gillespie, Chao Ma, Vladimir I. VladimirovAbstractIn recent years, large scale meta-analysis of genome-wide association studies (GWAS) have reliably identified genetic polymorphisms associated with neuropsychiatric disorders such as schizophrenia (SCZ), bipolar disorder (BPD) and major depressive disorder (MDD). However, the majority of disease-associated single nucleotide polymorphisms (SNPs) appear within functionally ambiguous non-coding g...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
CUPERTINO, Calif., April 25, 2019 -- (Healthcare Sales &Marketing Network) -- DURECT Corporation (Nasdaq: DRRX) announced today the appointment of two new members to its board of directors. Dr. Gail M. Farfel, Executive Vice President and Chief Developm... Biopharmaceuticals, Drug Delivery, Personnel DURECT, PERSERIS, risperidone, Schizophrenia
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
I spend half my week in a community clinic working with a lot of folks with schizophrenia or bipolar 1 so have fair number on SGAs either PO or LAI. I’m constantly getting lipid panels back that are off the chain, refer to primary care and seems less than 20% of patients ever actually go. Currently I would never consider prescribing statins because I’m not up on guidelines, but has gotten me starting to wonder. I can check any labs I want and presumably it’s not rocket science to follow... Would you ever consider prescribing statins?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Psychiatry Source Type: forums
 We all know what first aid is. Many of us even have first aid kits that we’ve purchased or put together ourselves. We pull them out when we have a minor injury and grab the bandages or whatever we need. But what about first aid for the mind? It’s not a kit you can pick up at the pharmacy, but there is mental health first aid that you can learn. Find out more about it in this episode.   Subscribe to Our Show! And Remember to Review Us! About Our Guest Michael Cox is a licensed professional counselor in the state of Texas and is the co-founder and therapist in private practice at Whole...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Mental Health and Wellness The Psych Central Show Gabe Howard mental health first aid Vincent M. Wales Source Type: blogs
Authors: Chen R, Liou TH, Miao NF, Chang KH, Yen CF, Liao HF, Chi WC, Chou KR Abstract Little is known about the changes of people with schizophrenia disability in Taiwan who receive routine treatments under the current mental healthcare system. The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) was used to assess and track changes in the degree of disability in people with schizophrenia before and after 4 years of follow-up. Data on 4497 people with schizophrenia were acquired from the Taiwan Data Bank of Persons with Disability. The WHODAS 2.0 was used for disability assessment, and the...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
CONCLUSIONS: There is evidence of declining continuity of care in this 11-year study of people with schizophrenia, and of an independent effect of this on worse clinical outcomes. We suggest that this is related to reorganisation of services.Declaration of interestNone. PMID: 31012407 [PubMed - in process]
Source: The British Journal of Psychiatry for Mental Science - Category: Psychiatry Tags: Br J Psychiatry Source Type: research
Conclusions: Prefrontal gyrification is reduced in children with ADHD who also carry the DRD4 7R allele, and it relates to critical functional skills in the executive domain in carriers of the risk allele. More broadly, these effects highlight the importance of considering precise neurodevelopmental mechanisms through which risk alleles influence cortical neurogenesis and migration.IntroductionAttention deficit/hyperactivity disorder (ADHD) is a heterogeneous neuropsychiatric disorder characterized by developmentally inappropriate symptoms of inattention, impulsivity, and hyperactivity. The disorder is thought to affect ar...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion: Some patients with psychiatric syndromes and increased ANA titers may suffer from psychiatric variants of SLE, even if the American College of Rheumatology criteria for SLE are not met. Whether the psychiatric symptoms in our patient represent a prodromal stage with the later manifestation of full-blown SLE or a subtype of SLE with isolated CNS involvement remains unclear. Regardless, early diagnosis and initiation of immunosuppressive treatment are essential steps in preventing further disease progression and organ damage. Intrathecal ANAs with extractable nuclear antigen differentiation may be a more sensitiv...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
This study is … the first, to our knowledge, to describe the correlates of subsequent injurious violence among patients being treated for schizophrenia in which the independent variables include recent violence toward others,” wrote Alec Buchanan, Ph.D., M.D, of Yale University School of Medi cine and colleagues.The analysis included 1,435 participants in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study. Researchers assessed participants ’ clinical condition and violent behavior at baseline and every six months for the duration of the 18-month study.Violent behavior was self-...
Source: Psychiatr News - Category: Psychiatry Tags: ajp in advance Alec Buchanan CATIE medication adherence schizophrenia violence Yale Source Type: research
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