Microstructural Changes in Higher-order Nuclei of the Thalamus in Patients with First-episode Psychosis

Disruption in the thalamus, such as volume, shape and cortical connectivity, is regarded as an important pathophysiological mechanism in schizophrenia. However, there is little evidence of nuclei-specific structural alterations in the thalamus during early-stage psychosis, mainly due to the methodological limitations of conventional structural imaging in identifying the thalamic nuclei.
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Archival Report Source Type: research