Effects of Restoring the Primary Dentition with Stainless-Steel Crowns on Children's Salivary Nickel and Chromium Levels, and the Associations with Saliva pH: a Preliminary Before-After Clinical Trial.

Effects of Restoring the Primary Dentition with Stainless-Steel Crowns on Children's Salivary Nickel and Chromium Levels, and the Associations with Saliva pH: a Preliminary Before-After Clinical Trial. Biol Trace Elem Res. 2018 May 23;: Authors: Basir L, Meshki R, Behbudi A, Rakhshan V Abstract Nickel and chromium existing in stainless-steel crowns (SSCs, used in pediatric dentistry) might be cytotoxic and allergenic. However, no in vivo studies have examined their salivary levels in children using SSCs, or in young children without SSCs. Also, the effect of acidity on metal ion release has not yet been evaluated in any previous in vivo studies in the whole literature. Therefore, this preliminary before-after clinical trial was conducted. Salivary nickel/chromium levels of 30 children before and after 2 months of placement of SSCs were measured using atomic absorption spectrophotometry. Salivary pH was measured with a digital pH meter. The effects of treatment, pH, number of SSCs, gender, and age on salivary ions were analyzed statistically (α = 0.05, β = 0.15). Salivary nickel concentrations increased from 4.9010 ± 4.7390 to 5.6320 ± 4.7210 μg/L (P = 0.000, paired t test). Chromium increased from 0.3273 ± 0.5214 to 0.4199 ± 0.6404 μg/L (P = 0.016). Saliva pH increased from 6.81 ± 0.52 to 7.04 ± 0.47 (P = 0.000). Ion levels were not correlated with pH (P > 0.14), except ...
Source: Biological Trace Element Research - Category: Biology Authors: Tags: Biol Trace Elem Res Source Type: research