Signs of impaired blood-brain barrier function and lower IgG synthesis within the central nervous system in patients with schizophrenia or related psychosis, compared to that in controls.

CONCLUSIONS: In this study we show that patients with schizophrenia or related psychosis have impaired BBB function and lower IgG synthesis within the CNS, compared to controls. These findings support the view that a pathological process within the CNS, combined with an aberrant immune system, may underlie the development of schizophrenia. PMID: 29803205 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29803205?dopt=Abstract

Source: Neuroendocrinology Letters - May 30, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research