Exercise related anxiety-like behaviours are mediated by TNF receptor signaling, but not depression-like behaviours.

DISCUSSION: Exercise associated TNFR1 and TNFR2 signaling in concert in WT exercise mice ice mediated reductions in aspects of anxiety-like behaviours. These findings are consistent with the current view that imbalances in TNF signaling are involved in disrupted affect. Additional studies are needed to further explore the roles of exercise related TNFR1 and TNFR2 signaling in anxiety-like and depression-like behaviours. PMID: 29800552 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29800552?dopt=Abstract

Source: Brain Research - May 22, 2018 Category: Neurology Authors: Morgan JA, Singhal G, Corrigan F, Jaehne EJ, Jawahar MC, Baune BT Tags: Brain Res Source Type: research