Auditory steady state response deficits are associated with symptom severity and poor functioning in patients with psychotic disorder

Gamma oscillation is important for cortico-cortical coordination and the integration of information across neural networks. The 40  Hz auditory steady-state response (ASSR), which reflects neural synchrony in the gamma band (30–100 Hz), is abnormal in patients with schizophrenia (SZ). The present study used the ASSR at multiple frequencies to examine (1) gamma dysfunction in patients with SZ, schizoaffective (SA), and bip olar disorder (BD) compared with controls, (2) the relationship between ASSR measures and clinical symptom severity, and (3) the relationship between ASSR measures and real-life community functioning.
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research