A review of novel technologies and techniques associated with identification of bloodstream infection aetiologies and rapid antimicrobial genotypic and quantitative phenotypic determination.

A review of novel technologies and techniques associated with identification of bloodstream infection aetiologies and rapid antimicrobial genotypic and quantitative phenotypic determination. Expert Rev Mol Diagn. 2018 May 23;: Authors: Poole S, Kidd SP, Saeed K Abstract Introduction The antimicrobial aspect of management of patients with blood stream infections (BSI) and sepsis is time critical. In an era of increasing antimicrobial resistance, rapid detection and identification of bacteria with antimicrobial susceptibility is crucial to direct therapy early in the course of illness. Molecular techniques offer a potential solution to this. Areas covered In the present review the authors have discussed a number of novel solutions utilising a variety of molecular techniques for pathogen detection, identification and antimicrobial susceptibility. The review is not designed to cover all solutions ever developed or be an exhaustive literature review, instead the authors have focused on what they have had experience using or currently view as new and exciting with potential to revolutionise BSI diagnosis. The authors searched PubMed (Medline) and Google Scholar with terms: BSI, Bacteraemia, Candidaemia, Diagnostics, AST, Rapid, AMR and Blood Culture. The authors attended recent clinical microbiology technology congresses. Expert commentary There are multiple exciting novel technologies at differing stages of development with potential to r...
Source: Expert Review of Molecular Diagnostics - Category: Laboratory Medicine Tags: Expert Rev Mol Diagn Source Type: research