Re: Almassi et  al.: Use of 99mTc-Sestamibi Single-photon Emission Computed Tomography / X-ray Computed Tomography in the Diagnosis of Hybrid Oncocytic / Chromophobe Tumor in a Pediatric Patient. (Urology 2018;113:206-208)

A recent reassessment of the pathology for the case described in this report has facilitated new perspectives, and our objective is to provide an update that should be informative.1 The patient was a 12-year-old girl with 2 right lower pole renal tumors, both relatively small ( ≤2.0 cm) and solid, and only demonstrating modest enhancement. Genetic testing revealed a defect in the fumarate hydratase (FH) gene, which is commonly altered in the hereditary leiomyomatosis renal cell carcinoma (HLRCC) syndrome, where aggressive renal tumors are typically seen.

Source: Urology - March 9, 2018 Category: Urology & Nephrology Authors: S.C. Campbell, J.K. McKenney, N. Almassi, M.A. Gorin, S.P. Rowe, A.S. Purysko, J. Kaouk, M.E. Allaf, A. Rhee Source Type: research