Exploration of (hetero)aryl derived thienylchalcones for antiviral and anticancer activities.

CONCLUSION: Compounds V and VI were demonstrated viral inhibition towards Human cytomegalovirus, whereas cyclopropylquinoline derivative IV towards Rift Valley fever virus and Tacaribe virus. Additionally, cyclopropylquinoline derivative IV has displayed very good cytotoxicity against colon, breast and leukemia cell lines in vitro. PMID: 29792154 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29792154?dopt=Abstract

Source: Medicinal Chemistry - May 23, 2018 Category: Chemistry Authors: Patil V, Patil SA, Patil R, Bugarin A, Beaman K, Patil SA Tags: Med Chem Source Type: research