Intravenous Thrombolysis in Patients with Acute Ischemic Stroke after a Reversal of Dabigatran Anticoagulation with Idarucizumab: A Real-World Clinical Experience
Intravenous thrombolysis (IVT) is contraindicated in patients with acute ischemic stroke (AIS) using oral anticoagulants. A specific human monoclonal antibody was introduced to reverse immediately the anticoagulation effect of the direct inhibitor of thrombin, dabigatran. Until now, mostly individual cases presenting with successful IVT after a reversal of dabigatran anticoagulation in patients with AIS were published. Thus, we aimed to report real-world data from clinical practice.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Daniel Šaňák, Stanislava Jakubíček, David Černík, Roman Herzig, Zdeněk Kunáš, Robert Mikulík, Svatopluk Ostrý, Michal Reif, Vladimír Rohan, Aleš Tomek, Tomáš Veverka Source Type: research