Prevalence and Clinicopathologic Significance of BRAF V600E Mutation in Chinese Multiple Myeloma Patients

On the basis of the study of 205 Chinese patients with multiple myeloma, we demonstrated a prevalence of 9.3% of BRAF V600E mutation, the highest hitherto reported. Additionally, BRAF V600E mutation was found to be associated with hypercalcemia and a male predominance. In subgroup analysis, the BRAF V600E mutation showed prognostic impact on overall survival in younger patients (

Source: Clinical Lymphoma, Myeloma and Leukemia - May 14, 2018 Category: Hematology Authors: Coty H.Y. Cheung, Chi Keung Cheng, Kin-Mang Lau, Rosalina K.L. Ip, Nelson C.N. Chan, Tommy H.C. Tam, Raymond S.M. Wong, Radha Raghupathy, Natalie P.H. Chan, Margaret H.L. Ng Tags: Original Study Source Type: research