FGF21 protects human umbilical vein endothelial cells against high glucose-induced apoptosis via PI3K/Akt/Fox3a signaling pathway

In this study, we aimed to investigate the protective capacity of FGF21 in human umbilical vein endothelial cells (HUVECs) against high glucose (HG)-induced apoptosis via phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt)/FoxO3a pathway.

Source: Journal of Diabetes and Its Complications - May 25, 2018 Category: Endocrinology Authors: Dongmin Guo, Lele Xiao, Huijun Hu, Mihua Liu, Lu Yang, Xiaolong Lin Source Type: research