Effect of different glucose-lowering therapies on cancer incidence in type 2 diabetes: an observational population-based study

Current epidemiological data suggest that patients with diabetes, in particular type 2 diabetes, have an increased risk of developing different types of neoplasms. [1,2] In particular, higher incidence has been observed for breast [2 –4], endometrial [2,5,6], pancreatic, colorectal [2,4,7] and liver cancer. [2,7] Metformin has become one of the most widely used drugs in the treatment of type 2 diabetes mellitus (T2DM) and is the first-line therapy for patients with T2DM according to the American Diabetes Association/European A ssociation for Study of Diabetes guidelines.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Tags: Invited review Source Type: research