Regulatory NK1.1 − CD4 + NKG2D + subset induced by NKG2DL + cells promotes tumor evasion in mice

In conclusion, we describe a regulatory NK1.1−CD4+NKG2D+ T-cell population, different from other regulatory T cells and abnormally elevated in pCD86-Rae-1 ε transgenic and MC38 tumor-bearing mice.
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research