Initial diagnosis of insignificant Cancer, HGPIN, ASAP and negative have the same rate of upgrade to Gleason ≥7 on repeat prostate biopsy

Extended prostate needle core biopsies are standard of care for the diagnosis of prostatic carcinoma. Subsequent biopsies may be performed for a variety of indications. Knowledge of biopsy characteristics indicating risk for progression may have utility to guide therapeutic management. Prostate needle core biopsies performed between 2008 –2014 were reviewed. Patients with at least 1 subsequent biopsy were identified. Cases were categorized by worst initial diagnosis. Gleason ≤6 carcinoma was further classified as significant or insignificant with insignificant defined as: ≤2 cores with carcinoma, sites with ≤50% carcinoma, a nd unilateral carcinoma.
Source: Human Pathology - Category: Pathology Authors: Tags: Original contribution Source Type: research