60  years of placebo-controlled antipsychotic drug trials in acute schizophrenia: Meta-regression of predictors of placebo response

A recent meta-regression had shown that the degree of placebo response, which has increased over the decades, is the major predictor of drug-placebo differences in antipsychotic drug trials in acutely ill patients with schizophrenia. Drug response, however, had remained stable. In the current meta-regression we explored the factors that are associated with placebo-response.

Source: Schizophrenia Research - May 24, 2018 Category: Psychiatry Authors: Stefan Leucht, Anna Chaimani, Claudia Leucht, Maximilian Huhn, Dimitris Mavridis, Bartosz Helfer, Myrto Samara, Andrea Cipriani, John R. Geddes, Georgia Salanti, John M. Davis Source Type: research