Assessment of the subtilisin genes in Trichophyton rubrum and Microsporum canis from dermatophytosis

This study showed the most frequency of SUB gene families (11/17). At least one virulence gene was observed for 94% (16/17) of the isolates. Statistical analysis revealed significant associations between SUB presence and isolates, origin of isolates (animal or human infection) and infection type (skin, hair, and nail) (P <  0.05). This is the first report on the presence/absence of SUB genes in isolates that were obtained from human and animal infection in Iran, which seems to raise the risk to be pathogenic.
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research