A Novel Small-Animal Model of Irradiated, Implant-Based Breast Reconstruction

Conclusions: The authors describe a novel small-animal model for irradiated, implant-based breast reconstruction where histologic analysis shows structural changes in the skin consistent with known effects of radiation therapy and expansion in human skin. This model represents a significant improvement from previous ones and, as such, holds the potential to be used to test new therapeutic agents to improve clinical outcomes.
Source: Plastic and Reconstructive Surgery - Category: Cosmetic Surgery Tags: Experimental: Original Articles Source Type: research