NEAT1 upregulates TGF ‐β1 to induce hepatocellular carcinoma progression by sponging hsa‐mir‐139‐5p

Journal of Cellular Physiology, EarlyView.
Source: Journal of Cellular Physiology - Category: Cytology Authors: Source Type: research

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ConclusionsTACE is a safe and effective procedure for liver tumor treatment. The majority of the complications are rare and present a low incidence of mortality.ResumenIntroducciónLa quimioembolización transarterial (QETA) es considerada una opción terapéutica utilizada en el tratamiento del carcinoma hepatocelular y de las metástasis hepáticas secundarias del carcinoma colorrectal, tumores neuroendocrinos y melanoma ocular. Aunque es un procedimiento seguro, no está exento de complicaciones, siendo la más frecuente la colecistitis aguda. Otras complicaciones descrita...
Source: Cirugia Espanola - Category: Surgery Source Type: research
ConclusionLMH is safe and feasible in elderly patients with HCC. However, LMH in elderly patients is associated with poorer perioperative outcomes compared to LMH in young patients. Comparison between LMH and OMH in elderly patients demonstrated advantages in terms of decreased pulmonary complications and shorter length of stay at the expense of increased operation time and blood loss.
Source: World Journal of Surgery - Category: Surgery Source Type: research
AbstractBackgroundThe aim of this study was to evaluate the feasibility of liver resection in hepatocellular carcinoma (HCC) patients with preoperative renal dysfunction (RD).MethodsData from 735 patients undergoing primary liver resection for HCC between 2002 and 2014 were analyzed. Short- and long-term outcomes were compared between the RD group, defined by a preoperative estimated glomerular filtration rate of
Source: World Journal of Surgery - Category: Surgery Source Type: research
In this study, sera samples, staged hepatic cancer tissues from Sor-treated patients with advanced HCC were harvested for a group of biochemical tests and immunoassays. Compared to non-treated control, blood contents of alanine transaminase (ALT), aspartate transaminase (AST), alphafetoprotein (AFP), fibroblast growth factor 21 (FGF21) were decreased in Sor-treated HCC patients, while the level of interleukin 10 (IL-10) were increased. As well, reduced triglyceride (TG), total cholesterol (T-CHOL), interferon gamma (IFN-γ), and tumor necrosis factor alpha (TNF-α) levels in sera were checked in Sor-treated HCC p...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
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Source: Cancer Science - Category: Cancer & Oncology Authors: Tags: Original Article Source Type: research
ConclusionTexture analysis based on preoperative MRI are potential quantitative predictors of ER in HCC patients after hepatectomy, and may provide more information for preoperative treatment decision-making and follow up.
Source: Academic Radiology - Category: Radiology Source Type: research
Publication date: Available online 9 November 2018Source: Arab Journal of GastroenterologyAuthor(s): Abd Elkhalek Hamed, Medhat Elsahar, Nadia M. Elwan, Sara Elnakib, Mervat Naguib, Hanan Hamed Soliman, Ashraf Ahmed Aboubakr, Amany AbdelMaqsod, Heba Sedrak, Samir N. Assaad, Reda Elwakil, Gamal Esmat, Samira Salh, Taymour Mostafa, Sherif Mogawer, Sameh Emil Sadek, Maha M. Saber, Hanan Ezelarab, Asem Ashraf Mahmoud, Souad SultanAbstractThere is strong association between liver diseases and diabetes (DM) which is higher than expected by a chance association of two very common disorders. It can be classified into three categor...
Source: Arab Journal of Gastroenterology - Category: Gastroenterology Source Type: research
Publication date: Available online 7 November 2018Source: Materials Science and Engineering: CAuthor(s): María J. Limeres, Marcela A. Moretton, Ezequiel Bernabeu, Diego A. Chiappetta, María L. CuestasAbstractNanotechnology has recently emerged as a promising tool in biomedicine research. An important branch of nanotechnology is drug delivery and drug targeting using a wide range of biomaterials with promising potential applications in cancer research. The aim of this review is to provide an overview of the evolution of nanotechnology in cancer therapy, exemplified by a myriad of applications in drug delivery,...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: Available online 1 November 2018Source: Materials Science and Engineering: CAuthor(s): Rong Liu, Huicong Zhang, Fangrong Zhang, Xuandong Wang, Xiaolong Liu, Yun ZhangAbstractThe nanoplatform of synergistic chemo-photothermal therapy has superior advantages on antitumor. It is urgently needed to explore novel nanocarrier for improving photothermal performance in drug delivery process. Herein, we synthesized polydopamine doped mesoporous silica-coated reduced graphene oxide (rGO/MSN/PDA) by simply adding dopamine hydrochloride into the oil-water biphasic reaction system as a multifunctional drug carrier for...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: Available online 10 November 2018Source: Carbohydrate PolymersAuthor(s): Haiyao Sun, Chunying Li, Yujiao Ni, Liping Yao, Hongwei Jiang, Xueting Ren, Yujie Fu, Chunjian ZhaoAbstractIn the present study, an efficient ultrasonic/microwave-assisted extraction (UMAE) procedure for the polysaccharides from the fruit of Camptotheca acuminata (CAFP) was investigated and optimized. Under the optimum conditions (ratio of liquid to raw material 30 mL/g, microwave irradiation time of 20 min, microwave irradiation power of 570 W and a fixed ultrasonic power of 50 W obtained by the response ...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
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