U.S. biotechs to speed work on Nipah vaccine as virus hits India

LONDON (Reuters) - A global coalition set up a year ago to fight epidemics has struck a $25 million deal with two U.S. biotech companies to accelerate work on a vaccine against the brain-damaging Nipah virus that has killed 12 people in India.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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Nipah virus is an emerging pathogenic paramyxovirus responsible for sporadic and isolated outbreaks of severe respiratory and neurologic disease in Southern Asia. As a zoonotic virus, disease can manifest in both animals and human with indigenous fruit bats acting as natural reservoirs of the virus. The effects of viral infection vary from acute respiratory distress to fatal encephalitis. There are currently no approved therapeutics or vaccines against the virus, and growing concerns that this highly pathogenic infection has the potential to cause larger epidemics capable of inflicting significant mortality burden.Like the...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
Authors: Ochani RK, Batra S, Shaikh A, Asad A Abstract The Nipah virus was discovered twenty years ago, and there is considerable information available regarding the specificities surrounding this virus such as transmission, pathogenesis and genome. Belonging to the Henipavirus genus, this virus can cause fever, encephalitis and respiratory disorders. The first cases were reported in Malaysia and Singapore in 1998, when affected individuals presented with severe febrile encephalitis. Since then, much has been identified about this virus. These single-stranded RNA viruses gain entry into target cells via a process k...
Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research
A global coalition set up to fight emerging epidemics has struck a $31 million deal with scientists at Japan's University of Tokyo to speed up work on a vaccine against a brain-damaging disease caused by the Nipah virus.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
(CNN) — From climate change to superbugs, the World Health Organization has laid out 10 big threats to our global health in 2019. And unless these threats get addressed, millions of lives will be in jeopardy. Here’s a snapshot of 10 urgent health issues, according to the United Nations’ public health agency: Not vaccinating when you can One of the most controversial recent health topics in the US is now an international concern. “Vaccine hesitancy — the reluctance or refusal to vaccinate despite the availability of vaccines — threatens to reverse progress made in tackling vaccine-prevent...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Local TV Source Type: news
Abstract We briefly review the situations arising out of epidemics that erupt rather suddenly, threatening life and livelihoods of humans. Ebola, Zika and the Nipah virus outbreaks are recent examples where the viral epidemics have led to considerably high degree of fatalities or debilitating consequences. The problems are accentuated by a lack of drugs or vaccines against the new and emergent viruses, and the inordinate amount of temporal and financial resources that are required to combat the novel pathogen. Progress in computational. biological and informational sciences have made it possible to consider design...
Source: Current Topics in Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Top Med Chem Source Type: research
LONDON (Reuters) - A global coalition set up a year ago to fight epidemics has struck a $25 million deal with two U.S. biotech companies to accelerate work on a vaccine against the brain-damaging Nipah virus that has killed at least 11 people in India.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
occur at all stages of life. They can represent disease at its primary site of replication (e.g. rabies) or be part of an infection syndrome (e.g. HIV). A large proportion of cases go unconfirmed by laboratory diagnosis despite use of all available laboratory techniques. They can be sporadic or epidemic, but with changing environmental and societal conditions, infective agents can emerge for the first time (e.g. Nipah, Hendra and Zika viruses) or reappear after a period of good control through vaccination (e.g.
Source: Medicine - Category: Internal Medicine Authors: Tags: Nervous system infections Source Type: research
Coalition for Epidemic Preparedness Innovations. 03/29/2017 This four-page document provides guidance on the completion of the CEPI questionnaire on regulatory science issues for development of emerging infectious disease (EID) vaccines. Partners with an interest in securing regulatory approval/licensure of EID vaccines are invited to provide comment on the regulatory scientific issues for the development of EID vaccines. The document provides background information and issues on the prioritized pathogens Ebola, Lassa, Nipah, and Middle East respiratory syndrome (MERS). (PDF)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Authors: Source Type: news
In the wake of the Ebola crisis that erupted in West Africa in 2014, many public health leaders recognized that a more aggressive effort to develop vaccines could have moved a vaccine forward more quickly and prevented that outbreak from becoming an epidemic. A new organization was formed last year, the Coalition for Epidemic Preparedness Innovations (CEPI), to speed development of vaccines against emerging infectious diseases—but it had no serious financial backing. Now, CEPI has attracted nearly a half-billion dollars in funding, as it planned to announce at the World Economic Forum in Davos, Switzerland, this...
Source: ScienceNOW - Category: Science Authors: Tags: Public Health Source Type: news
A global coalition of governments, health specialists and philanthropists will launch a new plan on Thursday to “outsmart” future disease epidemics with a fund to prepare and create new vaccines. Stung by the devastation of West Africa’s 2014-2015 Ebola outbreak, which killed more than 11,300 people before an effective vaccine was developed, the coalition is aiming to ensure such deadly outbreaks can’t happen again. John-Arne Rottingen, interim chief executive officer of the Coalition for Epidemic Preparedness Innovations (CEPI), said it is designed as “a global insurance policy against epidem...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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