Early Immunosuppressive Exposure of Enteric-Coated-Mycophenolate Sodium Plus Tacrolimus Associated with Acute Rejection in Expanded Criteria Donor Kidney Transplantation.

Conclusions: Low-level exposure of MPA and Tac C0in the early weeks posttransplant reflects an increased acute rejection risk, which suggested that MPA-AUC0-12h <30 mg·h-1·L-1 and Tac C0 <4 ng/ml should be avoided in the first few weeks after transplantation. PMID: 29786042 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/29786042?dopt=Abstract

Source: Chinese Medical Journal - May 24, 2018 Category: General Medicine Authors: Ding CG, Jiao LZ, Han F, Xiang HL, Tian PX, Ding XM, Pan XM, Tian XH, Li Y, Zheng J, Xue WJ Tags: Chin Med J (Engl) Source Type: research