Use of split ‐thickness plantar skin grafts in the management of leg and foot skin defects

International Wound Journal, EarlyView.
Source: International Wound Journal - Category: Surgery Authors: Source Type: research

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The objective of this study was to review the outcomes after split-thickness skin grafting (SSG) of patients with peripheral artery disease and diabetic foot wounds in an Asian population.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
Negative pressure wound therapy (NPWT) is a popular and effective adjunct treatment for a great variety of wounds including split-thickness skin graft (STSG). Studies have concluded that NPWT improves STSG uptake. Recent technologic advancements have led to the advent of a new generation of NPWTs. These are the disposable, ultraportable, and mechanically operated NPWTs designed to treat smaller wounds with low to moderate exudates.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
Abstract Follicular unit excision (FUE) requires the careful excision of hair-bearing follicular units. The follicle can only be detached from the skin once the epidermis, dermis, and subcutaneous tissues are cut, and each layer requires a different amount of force. Traditional FUE devices can be set only to a single speed during a single excision. The Trivellini Device is a first-in-class programmable multiphasic device that is able to accommodate the cutting of various layers of tissue in a single program, while ensuring minimal transection of hair grafts. We detail the advances in the field of motorized FUE emb...
Source: Skinmed - Category: Dermatology Authors: Tags: Skinmed Source Type: research
This study analyzed PCT and CRP levels of 214 pediatric patients with a median age of 8.5  years (0.4–17.8 years) undergoing allogeneic HSCT with respect to major TRAE.Results26 patients (12.1%) did not experience TRAE (control group), and 188 (87.9%) experienced median 2 (range 1 –4) TRAE. Median CRP and PCT were highly and significantly increased during sepsis/SIRS and bacteremia (17.24 mg/dl | 6.30 ng/ml;p 
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
In conclusion, ICH is a rare lesion composed of cutaneous elements in an abnormal location. A predilection for the buccal mucosa is reported in the current study.
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Original Study Source Type: research
Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, serves as a molecular battery for immune cells by storing and distributing energy to power their fight against cancer, according to new UCLA research.The study, conducted in mice and published in the Journal of Experimental Medicine, is the first to show that creatine uptake is critical to the anti-tumor activities of CD8 T cells, also known as killer T cells, the foot soldiers of the immune system. The researchers also found that creatine supplementation can improve the efficacy of existing immunotherapies.“Because oral ...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Conclusion: TA flap has a simple design that minimizes concerns involving the donor site. Moreover, it does not require complicated procedures and allows for re-elevation whenever necessary. Finally, it guarantees faster wound recovery than skin graft with fewer complications. PMID: 31620390 [PubMed]
Source: Annals of Surgical Treatment and Research - Category: Surgery Tags: Ann Surg Treat Res Source Type: research
Allogeneic hematopoietic stem cell transplant (allo-HSCT) is often used to treat acute leukemia or defects of hematopoiesis. Its widespread use is hampered by graft-vs.-host disease (GVHD), which has high morbidity and mortality in both acute and chronic subtypes. Chronic GVHD (cGVHD) occurs most frequently in skin and often is characterized by pathogenic fibrosis. Mast cells (MCs) are known to be involved in the pathogenesis of other fibrotic diseases. In a murine model of cGVHD after allo-HSCT, C57BL/6J recipients of allogeneic LP/J donor cells develop sclerodermatous dermal cGVHD which is significantly decreased in mast...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
ConclusionThis systematic review and meta-analysis indicate that it is effective and safe to use AM for treating STSGDS.
Source: Burns - Category: Dermatology Source Type: research
The objective of this study was to evaluate where and when pediatric burn injuries occurred. Furthermore the quality of first aid treatment, ratio of skin grafting and length of hospital stay were evaluated. The patient records of 749 children with acute b...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news
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