Efficacy and Safety of Curcumin in Treatment of Intestinal Adenomas in Patients with Familial Adenomatous Polyposis

Familial adenomatous polyposis is an autosomal dominant disorder characterized by development of hundreds of colorectal adenomas and eventually colorectal cancer. Oral administration of the spice curcumin has been followed by regression of polyps in patients with this disorder. We performed a double-blind, randomized trial to determine the safety and efficacy of curcumin in patients with familial adenomatous polyposis.

Source: Gastroenterology - May 23, 2018 Category: Gastroenterology Authors: Marcia Cruz-Correa, Linda M. Hylind, Jessica Hernandez Marrero, Marianna L. Zahurak, Tracy Murray-Stewart, Robert A. Casero, Elizabeth A. Montgomery, Christine Iacobuzio-Donahue, Lodewijk A. Brosens, G. Johan Offerhaus, Asad Umar, Luz M. Rodriguez, Franci Source Type: research