Impact of Baseline Central Retinal Thickness on Outcomes in the VIVID-DME and VISTA-DME Studies.
Impact of Baseline Central Retinal Thickness on Outcomes in the VIVID-DME and VISTA-DME Studies. J Ophthalmol. 2018;2018:3640135 Authors: Midena E, Gillies M, Katz TA, Metzig C, Lu C, Ogura Y Abstract Purpose: To report the impact of baseline central retinal thickness (CRT) on outcomes in patients with diabetic macular edema (DME) in VIVID-DME and VISTA-DME. Methods: Post hoc analyses of two randomized controlled trials in which 862 DME patients were randomized 1 : 1 : 1 to treatment with intravitreal aflibercept 2.0 mg every 4 weeks (2q4), intravitreal aflibercept 2.0 mg every 8 weeks after five initial monthly doses (2q8), or macular laser photocoagulation at baseline and as needed. We compared visual and anatomical outcomes in subgroups of patients with baseline CRT
CONCLUSION:: To conclude, the outcomes of radiocephalic arteriovenous fistulas created by nephrologists are at par with historic outcomes. PMID: 30784345 [PubMed - as supplied by publisher]
The effect of meal on blood glucose concentration is a key issue in diabetes mellitus because its estimation could be very useful in therapy decisions. In the case of type 1 diabetes mellitus (T1DM), the therapy based on automatic insulin delivery requires a closed-loop control system to maintain euglycaemia even in the postprandial state. Thus, the mathematical modelling of glucose metabolism is relevant to predict the metabolic state of a patient. Moreover, the eating habits are characteristic of each person, so it is of interest that the mathematical models of meal intake allow to personalise the glycaemic state of the ...
DIABETES type 2 risk could be lowered by making some diet or lifestyle changes. You could prevent high blood sugar symptoms and signs by making these small changes to your usual Chinese or Indian takeaway order.
An MIT-led research team has developed a drug capsule -- about the size of a blueberry -- that could be used to deliver oral doses of insulin, potentially replacing the injections that people with Type 1 diabetes have to give themselves every day. In tests in animals, the researchers showed that ...This is an NSF Multimedia Gallery item.
Ruifeng Shi, Yanping Wang, Xiaofei An, Jianhua Ma, Tongzhi Wu, Xiaojin Yu, Su Liu, Liji Huang, Lijuan Wang, Jingshun Liu, Jing Ge, Shanhu Qiu, Han Yin, Xiaolai Wang, Yao Wang, Bingquan Yang, Jiangyi Yu, Zilin Sun
CONCLUSIONS: The results for diabetic foot prevention knowledge and practices are not very encouraging. In light of this situation, primary care programs are important, where nurses provide effective education, as a mechanism for modifying the behavior of people with diabetes mellitus. PMID: 30785550 [PubMed - in process]
CONCLUSIONS: Most participants reported having healthy life habits, which they believe influence on disease control. Among the investigated parameters, only the habit of not smoking was associated with the absence of hypertensive peaks; the other habits did not present statistical association with the comorbidities. PMID: 30785546 [PubMed - in process]
CONCLUSION: The results show that there is a delay in wound healing in diabetic patients. PMID: 30785542 [PubMed - in process]
AbstractPurpose of ReviewMODY6 due to mutations in the gene NEUROD1 is very rare, and details on its clinical manifestation and pathogenesis are scarce. In this review, we have summarized all reported cases of MODY6 diagnosed by genetic testing, and examined their clinical features in detail.Recent FindingsMODY6 is a low penetrant MODY, suggesting that development of the disease is affected by genetic modifying factors, environmental factors, and/or the effects of interactions of genetic and environmental factors, as is the case with MODY5. Furthermore, while patients with MODY6 can usually achieve good glycemic control wi...