The diagnostic role of BAP1 in serous effusions

The aim of this study was to analyze the diagnostic role of BAP1 in effusion cytology. Effusions (n=258), consisting of 53 malignant mesotheliomas and 205 other cancers, the majority carcinomas (62 breast, 60 ovarian, 31 lung, 51 carcinomas of other origin, 1 melanoma), were analyzed for BAP1 expression using immunohistochemistry. BAP1 was lost in 46 (87%) mesotheliomas, compared to 4/205 (2%) loss in other cancers (P
Source: Human Pathology - Category: Pathology Authors: Tags: Original Contributions Source Type: research