NLM Informatics and Data Science Lecture Series: Semantic Annotations, Reuse, and Reproducibility

NLM Informatics and Data Science Lecture Series Biomodeling (or biosimulation modeling) has the potential to revolutionize patient-specific health care and precision medicine. To increase our knowledge and management of complex pathologies, biomodeling provides the ability to produce detailed, mechanistic simulations of the dynamic biological processes and their participants. The development of these biomodels can be viewed as analogous to software development. To be effective and to scale to larger systems, the models must include clear documentation (semantic annotations), be developed in a reproducible manner, and be designed to allow for plug-and-play reuse so that researchers can build from the efforts of others. In the presentation, Dr. Gennari will report on his group ’ s efforts to standardize practices for semantic annotation, and to demonstrate the value of those annotations both for semantic searching over model repositories and for model merging and model reuse tasks. Over the last several years, they have succeeded in building community-wide agreement on both the importance of semantic annotation and the format of these annotations. In addition, using their annotation and model reuse tool, they have developed several demonstration examples of model merging that leverage the use of semantic annotation. Finally, as an important consequence of their work, he will also report on the initiation of a new Center for Reproducible Biomedical Modeling. Brief Bio: John...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video