Enhancing fatty acid utilization ameliorates mitochondrial fragmentation and cardiac dysfunction via rebalancing optic atrophy 1 processing in the failing heart

ConclusionsThese findings demonstrate that enhancing FA utilization ameliorates mitochondrial fragmentation and cardiac dysfunction via rebalancing OPA1 processing in pressure overload-induced HF, suggesting a unique metabolic intervention approach to improving cardiac functions in HF.

https://academic.oup.com/cardiovascres/article/114/7/979/4911559?rss=1

Source: Cardiovascular Research - February 27, 2018 Category: Cardiology Source Type: research