Genotoxic Effects in Human Fibroblasts Exposed to Microwave Radiation.

Genotoxic Effects in Human Fibroblasts Exposed to Microwave Radiation.
Health Phys. 2018 Jul;115(1):126-139
Authors: Franchini V, Regalbuto E, De Amicis A, De Sanctis S, Di Cristofaro S, Coluzzi E, Marinaccio J, Sgura A, Ceccuzzi S, Doria A, Gallerano GP, Giovenale E, Ravera GL, Bei R, Benvenuto M, Modesti A, Masuelli L, Lista F
Abstract
In the last decades, technological development has led to an increasing use of devices and systems based on microwave radiation. The increased employment of these devices has elicited questions about the potential long-term health consequences associated with microwave radiation exposure. From this perspective, biological effects of microwave radiation have been the focus of many studies, but the reported scientific data are unclear and contradictory. The aim of this study is to evaluate the potential genotoxic and cellular effects associated with in vitro exposure of human fetal and adult fibroblasts to microwave radiation at the frequency of 25 GHz. For this purpose, several genetic and biological end points were evaluated. Results obtained from comet assay, phosphorylation of H2AX histone, and antikinetochore antibody (CREST)-negative micronuclei frequency excluded direct DNA damage to human fetal and adult fibroblasts exposed to microwaves. No induction of apoptosis or changes in prosurvival signalling proteins were detected. Moreover, CREST analysis showed for both the cell lines an increase in ...

Source: Health Physics - May 23, 2018 Category: Physics Authors: Franchini V, Regalbuto E, De Amicis A, De Sanctis S, Di Cristofaro S, Coluzzi E, Marinaccio J, Sgura A, Ceccuzzi S, Doria A, Gallerano GP, Giovenale E, Ravera GL, Bei R, Benvenuto M, Modesti A, Masuelli L, Lista F Tags: Health Phys Source Type: research