Tetramethylpyrazine attenuates lipopolysaccharide-induced cardiomyocyte injury via improving mitochondrial function mediated by 14-3-3 γ.

In conclusion, the cardioprotection of TMP against LPS-induced injury was through up-regulating the expression of 14-3-3γ, promoting the translocation of Bcl-2 to mitochondria, and improving the function of mitochondria.
PMID: 29782860 [PubMed - as supplied by publisher]

Source: European Journal of Pharmacology - May 18, 2018 Category: Drugs & Pharmacology Authors: Huang B, You J, Qiao Y, Wu Z, Liu D, Yin D, He H, He M Tags: Eur J Pharmacol Source Type: research