Medical News Today: Novel gel regrows brain tissue after stroke

In a first-of-its kind study, researchers show that a bioengineered gel can help brain tissue to regrow and restore function following a stroke.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Stroke Source Type: news

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Study Objectives:The role of obstructive sleep apnea (OSA) in the overall outcome of ruptured intracranial aneurysms (RIAs) is unknown. We have investigated the role of OSA in overall outcome of RIAs.Methods:Data from 159 consecutive patients were retrospectively reviewed. A chi-square test and regression analysis were performed to determine the significant difference. A value ofP
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
This study evaluated whether specific actual performance could accurately predict body function levels and upper limb use in the real-life functioning of poststroke hemiparesis patients to aid in choosing the most appropriate rehabilitation exercises. Methods: We measured the time taken for poststroke patients to move small objects with the paralyzed hand and investigated how the measurement could estimate upper extremity motor impairment and hand usage during activities of daily living (ADL). We examined 86 stroke patients (age 66 ± 16 years) whose upper extremity motor paralysis was measured usi...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Abstract Major efforts are currently made promoting neuronal plasticity and brain remodeling in the postacute stroke phase. Experimental studies evaluating new stroke therapies are mostly performed in rodents, which compared to humans exhibit a short lifespan. These studies widely employ young, otherwise healthy, rodents that lack the vascular risk factors and comorbidities of stroke patients. These risk factors compromise postischemic neurological recovery and brain plasticity and in several contexts reduce the brain responsiveness to recovery-inducing plasticity-promoting treatments. By examining risk factor mod...
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
Abstract Objective: To explore the effects of transcranial direct current stimulation (tDCS) on the motor recovery of stroke patients and the effect differences between the upper limb and lower limb. Methods: Randomized control trials published until January 2019 were searched from PubMed, Embase, ScienceDirect, and Cochrane Library databases. The standardized mean difference (SMD) with 95% confidence interval (CI) was estimated separately for upper and lower limb motor outcomes to understand the mean effect size. Results: Twenty-nine studies with 664 subjects were included in this meta-analysis. The ove...
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
Journal Name: Journal of Imagery Research in Sport and Physical Activity Issue: Ahead of print
Source: Journal of Imagery Research in Sport and Physical Activity - Category: Sports Medicine Source Type: research
This study is registered with Clinicaltrials.gov, NCT01335087 and is now closed.FindingsBetween April 25, 2011, and Feb 2, 2018, a total of 2834 patients with ACS had respiratory polygraphy, of whom 2551 (90·01%) were recruited. 1264 (49·55%) patients had OSA and were randomly assigned to the CPAP group (n=633) or the UC group (n=631). 1287 (50·45%) patients did not have OSA, of whom 603 (46·85%) were randomly assigned to the reference group. Patients were followed up for a median of 3·35 years (IQR 1·50–5·31). The prevalence of cardiovascular events was similar in the...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Publication date: Available online 12 December 2019Source: Heart &LungAuthor(s): Eeeseung Byun, Ruth Kohen, Kyra J. Becker, Catherine J. Kirkness, Sandeep Khot, Pamela H. MitchellAbstractBackgroundSleep-related impairment is a common but under-appreciated complication after stroke and may impede stroke recovery. Yet little is known about factors associated with sleep-related impairment after stroke.ObjectiveThe purpose of this analysis was to examine the relationship between stroke impact symptoms and sleep-related impairment among stroke survivors.MethodsWe conducted a cross-sectional secondary analysis of a baseline ...
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
Publication date: February 2020Source: The Arts in Psychotherapy, Volume 67Author(s): Laura L. Wood, Dani Bryant, Kerryann Scirocco, Hia Datta, Susan Alimonti, Dave MowersAbstractAphasia, most often caused by brain damage due to stroke, is a language disorder hindering one's ability to verbally express and/or comprehend language, ranging in severity from mild to severe. An Applied Thematic Analysis (ATA) was undertaken of a post-production focus group to evaluate a 12-week pilot program that used the CoActive Therapeutic Theater (CoATT) Model for persons in Aphasia recovery. Results of a focus group interview found five th...
Source: Arts in Psychotherapy - Category: Psychiatry & Psychology Source Type: research
Authors: Ashrafi MR, Amanat M, Garshasbi M, Kameli R, Nilipour Y, Heidari M, Rezaei Z, Tavasoli AR Abstract Introduction: Leukodystrophies constitute heterogenous group of rare heritable disorders primarily affecting the white matter of central nervous system. These conditions are often under-appreciated among physicians. The first clinical manifestations of leukodystrophies are often nonspecific and can occur in different ages from neonatal to late adulthood periods. The diagnosis is, therefore, challenging in most cases.Area covered: Herein, the authors discuss different aspects of leukodystrophies. The authors used...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research
Publication date: Available online 24 September 2019Source: Canadian Journal of DiabetesAuthor(s): Vincent C. WooAbstractAdults with type 2 diabetes mellitus can benefit from pharmacotherapies that lower their risk for cardiovascular disease. This review describes the salient findings from sodium-glucose cotransporter-2 (SGLT2) inhibitor cardiovascular outcome trials that serendipitously revealed the cardiorenal benefits of SGLT2 inhibitors in adults with type 2 diabetes mellitus who either have established cardiovascular disease or multiple cardiovascular risk factors. It also summarizes the findings from other phase 3 cl...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
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