FDA Approves Aimovig (erenumab-aooe) as a Preventive Treatment for Migraine

May 17, 2018 -- The U.S. Food and Drug Administration today approved Aimovig (erenumab-aooe) for the preventive treatment of migraine in adults. The treatment is given by once-monthly self-injections. Aimovig is the first FDA-approved preventive...
Source: Drugs.com - New Drug Approvals - Category: Drugs & Pharmacology Source Type: news

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This study was aimed to report the clinical profile, complications and risk factors associated with severe illness in patients with scrub typhus, outside the intensive care setting. Methods: It was a prospective study, which involved recruitment of patients with acute febrile illness and diagnosed to have scrub typhus, who were admitted to the general medical wards of a tertiary care centre in Kanchipuram district, in semi-urban south India, over a 12 month period between June 2015 and May 2016. The diagnosis was established both clinically (with or without pathognomonic eschar) and by a positive test of IgM antibodies...
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research
Migraine headaches are a chronic neurological disease condition. Migraines are not benign in that they are the number one leading cause of temporary total disability in the United States. Worldwide, migraines are reported as being one of the top 10 leading causes of disability. It is estimated that there are 38 million migraine sufferers in the United States and over 1 billion worldwide. Migraine headaches are characterized by pain occurring on one side of the head or the other. The pain is moderate to severe in nature, generally limiting activities. Associated symptoms are light and sound sensitivity with some patients h...
Source: Sarasota Neurology - Category: Neurology Authors: Tags: Migraines / Headache Uncategorized Aimovig CGRP headache specialist headaches migraine prevention receptor blocker Source Type: blogs
CONCLUSION: PFO closure might be beneficial in migraine patients by reducing migraine attacks and migraine days, especially in patients whose majority of migraine attacks are with aura. However, those benefits were not associated with an improvement in responders' rate or complete resolution of migraine; raising concerns on the magnitude of clinical benefit of PFO closure in migraine prevention. PMID: 29914296 [PubMed - as supplied by publisher]
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
Updated Date: Jun 20, 2018 EST
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
AbstractVertebral artery laceration/dissection (VALD) resulting in fatal subarachnoid hemorrhage (SAH) is a rare, but well-known phenomenon encountered in the forensic setting. Delayed ruptures are exceptionally rare, and pose several challenges to the forensic pathologist. In this paper we present a case of a 47-year-old male who collapsed suddenly following recent complaints of a headache and a reported seizure. He had a reported history of potential head trauma that occurred several days prior. Attempts at resuscitation were unsuccessful, and an autopsy examination was ordered. Computer tomography (CT), autopsy, histolo...
Source: Forensic Science, Medicine, and Pathology - Category: Forensic Medicine Source Type: research
Source: CNS Drugs - Category: Neurology Source Type: research
Primary care visits are never quick; we don’t give much advice over the phone or online; and we prioritize the government’s and insurance companies’ public health agenda over our own patients’ concerns. Imagine health care as a retail customer experience for a few minutes: Imagine you’re going to Walmart to buy a bag of dog food, a new coffee maker or to equip a small kitchen in your newly built mother-in-law apartment. 1. You’ve bought dog food there before, so you know exactly where it is. You just want to quickly grab a bag and get out of there. 2. You have a rough idea of where the c...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Policy Primary Care Source Type: blogs
When someone has chest pain and a headache at the same time, the causes are usually unrelated. However, some conditions can cause both symptoms. We explain these conditions here. We also discuss when chest pain and a headache might be due to issues relating to the heart or blood pressure, and when to see a doctor.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news
Plus, what you can do about them.
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
AbstractLisdexamfetamine dimesylate (lisdexamfetamine; Elvanse®; Tyvense®), an orally-active dexamfetamine prodrug, is indicated in the EU for the treatment of attention-deficit hyperactivity disorder (ADHD) in children aged  ≥ 6 years (including adolescents) when the response to previous methylphenidate (MPH) treatment is clinically inadequate. The original approval of the drug was based on the results of phase III trials in children and adolescents with ADHD who had an inadequate response to previous pharmacoth erapy (e.g. MPH) or were treatment naïve. In these studies, short-term treat...
Source: Drugs - Category: Drugs & Pharmacology Source Type: research
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