Design and synthesis of (aza)indolyl maleimide-based covalent inhibitors of glycogen synthase kinase 3[small beta]

Org. Biomol. Chem., 2018, Advance Article DOI: 10.1039/C8OB00642C, PaperZhimin Yang, Hui Liu, Botao Pan, Fengli He, Zhengying Pan The optimization of both non-covalent interactions and reactive groups led to azaindolyl maleimide compound38b as a selective and covalent inhibitor against GSK3[small beta]. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research