Gone but not forgotten: resolution of childhood kidney disease and the risk of end-stage kidney disease in adults

Primary glomerular diseases and congenital anomalies of the kidney and urinary tract are the most common causes of kidney disease in children. Although the short-term prognosis is favorable after clinical remission of nephrotic syndrome or successful surgical intervention for congenital anomalies, few studies have evaluated the implications of these and other childhood kidney diseases on the long-term risk of end-stage kidney disease (ESKD). Previous studies have suggested an increased risk of chronic kidney disease (CKD) or kidney function decline in children with a single functioning kidney, children who recover from acute kidney injury in the setting of critical illness, and children with Henoch-Schonlein nephritis or hemolytic uremic syndrome1-4; however, none of these studies included a control group, and most were small or of short duration.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Nephrology Digest Source Type: research