CgMED3 affects cell size and budding index to coordinate Candida glabrata cell growth.

In conclusion, we report that CgMed3AB functions as a wheel responsible for driving cellular acetyl-CoA metabolism, indirectly inducing the transcription of Cgcln3 and coordinating cell growth (Fig. 1). We propose that mediator subunits may represent a vital regulatory target modulating cell growth in C. glabrata. PMID: 29776932 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29776932?dopt=Abstract

Source: Applied and Environmental Microbiology - May 18, 2018 Category: Microbiology Authors: Liu H, Kong L, Qi Y, Chen X, Liu L Tags: Appl Environ Microbiol Source Type: research