The diagnostic value of using combined MR diffusion parameters to differentiate between low- and high-grade meningioma.

CONCLUSION: This study shows that combined MR diffusion parameters consisting of ADCmin, RD, and FA can differentiate high-grade from low-grade meningioma with a diagnostic accuracy of 96.2%. Advances in knowledge: To the best of our knowledge, this is the first study reporting that a combined use of all MR diffusion parameters provides higher diagnostic accuracy for the differentiation of low- from high-grade meningioma. Our study shows that any of the model combinations was superior to use of any individual MR diffusion parameters for differentiation between low and high grade meningioma. A combination of ADCmin, RD, and FA was found to be the best model for differentiating low-grade from high-grade meningioma and sensitivity, specificity, and AUC values were found to be 92.3%, 100%, and 0.96, respectively. Thus, a combination of MR diffusion parameters can provide more accurate diagnostic information when differentiation between low and high grade meningioma.
PMID: 29770735 [PubMed - as supplied by publisher]

Source: The British Journal of Radiology - May 17, 2018 Category: Radiology Authors: Aslan K, Gunbey HP, Tomak L, Incesu L Tags: Br J Radiol Source Type: research