Application of stem cells in denstistry for bone regeneration.

Application of stem cells in denstistry for bone regeneration. J Physiol Pharmacol. 2018 Feb;69(1):23-33 Authors: Brozek R, Kurpisz M, Koczorowski R Abstract Stem cells constitute a non-specialised cell pool able for proliferation, self-renewal and differentiation into progeny constantly replacing used up tissue and/or organ fragments. They have been observed to be present in many tissue reservoirs, including stomatognathic system. Oral cavity seems to be a particularly attractive stem cells' source as these cells are richly present and easily accessible in dental and periodontal tissues and they can be used for therapeutic purposes. Their application is also morally and ethically non-controversial. Bone tissue structure restoration together with restoring its weight-bearing and nutritive function depend on the proper function of stem cells supported with other techniques including tissue engineering. Traditionally, bone regeneration means bone restoration supported by newly formed bones supplied by stem cells of tissue reservoir. It may be also indispensable to create a scaffold which may support the bone formation facilitating the transportation of cells and cell stimulating molecules involving both the matrix and bone-forming cells. The regenerative potential of stem cells present in oral cavity can be used, for instance, to restore maxillary and mandibular bones. The bones support natural teeth or prostheses and regress as soon a...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research