Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology

Prior studies in C. elegans demonstrated that the expression of aggregation-prone polyglutamine proteins in muscle wall cells compromised the folding of co-expressed temperature-sensitive proteins, prompting inte...

Source: Molecular Neurodegeneration - May 18, 2018 Category: Neurology Authors: Michael C. Pace, Guilian Xu, Susan Fromholt, John Howard, Benoit I. Giasson, Jada Lewis and David R. Borchelt Tags: Research article Source Type: research