Cortical thickness correlates of minor neurological signs in patients with first episode psychosis

Neurological soft signs (NSS) are subtle abnormalities of motor and sensory function that are present in the absence of localized brain pathological lesions. In psychoses they have been consistently associated with a distinct pattern of cortical and subcortical brain structural alterations at the level of the heteromodal cortex and basal ganglia. However, a more specific and accurate evaluation of the cytoarchitecture of the cortical mantle could further advance our understanding of the neurobiological substrate of psychosis.

Source: Schizophrenia Research - May 18, 2018 Category: Psychiatry Authors: Simone Ciufolini, Maria Francesca Ponteduro, Tiago Reis-Marques, Heather Taylor, Valeria Mondelli, Carmine M. Pariante, Stefania Bonaccorso, Raymond Chan, Andy Simmons, Anthony David, Marta Di Forti, Robin M. Murray, Paola Dazzan Source Type: research