New single capsule of bismuth, metronidazole and tetracycline given with omeprazole versus quadruple therapy consisting of bismuth, omeprazole, amoxicillin and clarithromycin for eradication of Helicobacter pylori in duodenal ulcer patients: a Chinese prospective, randomized, multicentre trial

ConclusionsThe new single-capsule OBMT quadruple therapy is as effective and well tolerated as the widely used OBAC therapy for treatment ofH. pylori in clinical practice in China. In addition, this OBMT therapy largely overcomesH. pylori metronidazole and clarithromycin resistance.
Source: Journal of Antimicrobial Chemotherapy - Category: Microbiology Source Type: research