Polyphenols, their metabolites and derivatives as drug leads.

Polyphenols, their metabolites and derivatives as drug leads.
Curr Pharm Des. 2018 May 15;:
Authors: Almeida FA, Dos Santos CN, Ventura MR
Abstract
In this non-comprehensive review, the potential of natural polyphenols as lead compounds for the design and synthesis of new molecules with potential application in several diseases was highlighted. Organic synthesis has been essential for the development of new analogues of naturally found polyphenols, providing a wide range of structural modifications for structure-activity relationship studies and improving or modulating the biological activity of the promising compounds.
PMID: 29766784 [PubMed - as supplied by publisher]

Source: Current Pharmaceutical Design - May 15, 2018 Category: Drugs & Pharmacology Authors: Almeida FA, Dos Santos CN, Ventura MR Tags: Curr Pharm Des Source Type: research