Abuse-Deterrent Opioid Formulations Abuse-Deterrent Opioid Formulations

How do abuse-deterrent opioid formulations work--and are they effective? This review details the mechanisms and pharmacology of 10 abuse-deterrent formulations currently approved in the US.Anesthesiology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Pharmacist Journal Article Source Type: news

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ConclusionsSBES is safe and effective, with minimal morbidity. SBES has the potential advantages of shorter operative time, reduced anesthesia, and reduced hospital time, which can benefit patients, surgeons, and health care systems.Patient summarySimultaneous bilateral endoscopic surgery is an effective treatment with low complication rates for bilateral urolithiasis. This innovative and complicated procedure should be performed in high-volume centers by experienced surgeons.
Source: European Urology - Category: Urology & Nephrology Source Type: research
This study aimed to evaluate the effects of sevoflurane on working memory of rats and to characterize functional connectivity between excitatory neurons in the prefrontal cortex (PFC) during working memory performance.Methods18-month-old and 3-month-old male SD rats were implanted with a multielectrode array in the PFC. After recovery from the surgery, the aged and adult rats were divided into sevoflurane group and control group, respectively. Rats in sevoflurane group were exposed to 1 minimum alveolar concentration (MAC) or 1.5 MAC sevoflurane for two hours. At day1, 3, and 7 after exposure, the effects of sevoflurane an...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 20 July 2018Source: Trends in Anaesthesia and Critical CareAuthor(s): Richard Christie, Alex Kennedyh
Source: Trends in Anaesthesia and Critical Care - Category: Anesthesiology Source Type: research
Publication date: Available online 20 July 2018Source: Brazilian Journal of Anesthesiology (English Edition)Author(s): Bruno Mendes Carmona, Clauber Claudino Alves Almeida, Waldônio de Brito Vieira, Mario de Nazareth Chaves Fascio, Lídia Raquel de Carvalho, Luiz Antonio Vane, Fabiano Timbó Barbosa, do Nascimento Junior Paulo, Norma Sueli Pinheiro MódoloAbstractBackgroundAdequate preoperative fasting is critical in preventing pulmonary aspiration of gastric content. We proposed to study the sonographic gastric content dynamics after the ingestion of liquid or solid food in healthy volunteers and c...
Source: Brazilian Journal of Anesthesiology - Category: Anesthesiology Source Type: research
ConclusionsImplementation of a multifaceted intervention improved rates of guideline-concordant redosing of intraoperative prophylactic antibiotics.Graphical abstract
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
CONCLUSION: This small study showed that visual distraction should be considered as a simple and cost-effective alternative to local anaesthetic for flexible laryngoscopy. PMID: 30022747 [PubMed - as supplied by publisher]
Source: Journal of Laryngology and Otology - Category: ENT & OMF Tags: J Laryngol Otol Source Type: research
CONCLUSIONS: Propofol inhibits viability and induces apoptosis of A549 cells via an ERK1/2-dependent PUMA signaling. PMID: 30024623 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
A guest column by the American Society of Anesthesiologists, exclusive to KevinMD.com. It’s officially that time of year. Summer is in full-swing, and all of America is getting ready to take a much-needed holiday. However, some Americans, particularly those who suffer from chronic pain, often dread getting away. They are afraid their chronic pain might prevent them from having a good and restful vacation. They ask, “Will the long flight wreak havoc on my back?” Some of my patients even forgo trying to get away on holiday due to these fears. Other patients fear going away on a vacation because th...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Pain Management Primary Care Source Type: blogs
The aim of the present meta-analysis was to systematically examine the literature and to identify of the results of randomized controlled trials (RCTs) comparing the efficacy and safety of regional anesthesia (RA) versus general anesthesia (GA) for percutaneous nephrolithotomy (PCNL). An exhaustive electronic literature search of PubMed, Embase, and Web of science was performed until March 2018. Nine prospective RCTs concluding 858 patients comparing the use of RA to GA for PCNL were included. Combined results demonstrated that PCNL under RA could reduce operative time (mean difference [MD] –6.20; 95% CI –10.39...
Source: Urologia Internationalis - Category: Urology & Nephrology Source Type: research
Conditions:   Cesarean Delivery Affecting Newborn;   Anesthesia;   Inflammatory Response Intervention:   Diagnostic Test: HSCRP and NLR Sponsor:   Ufuk University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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