From the pages of allergywatch July 2018

In patients with chronic rhinosinusitis with nasal polyps (CRSwNP), type 2 inflammation and tissue eosinophilia suggest a poor prognosis, including increased postoperative recurrence risk. Recent studies have found that proton pump inhibitors (PPIs) can suppress production of the eosinophil chemoattractant eotaxin-3. The authors assessed the role of Th2 mediators in CRSwNP, along with the effects of eotaxtin 3 inhibition using PPIs.

Source: Annals of Allergy, Asthma and Immunology - May 17, 2018 Category: Allergy & Immunology Authors: Stanley M. Fineman, David A. Khan, Chitra Dinakar, David Michael Lang, Stephen A. Tilles Tags: Special Series Source Type: research