NEAT1 contributes to breast cancer progression through modulating miR ‐448 and ZEB1

Journal of Cellular Physiology, EarlyView.
Source: Journal of Cellular Physiology - Category: Cytology Authors: Source Type: research

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Authors: Zhang Z, Serrano-Negrón JE, Martínez JA, Baksi K, Banerjee DK Abstract Dolichol phosphate mannose synthase (DPMS) is an inverting GT-A-folded enzyme and classified as GT2 by CAZy. DPMS sequence carries a metal-binding DXD motif, a PKA motif, and a variable number of hydrophobic domains. Human and bovine DPMS possess a single transmembrane domain, whereas that from S. cerevisiae and A. thaliana carry multiple transmembrane domains and are superimposable. The catalytic activity of DPMS is documented in all spheres of life, and the 32kDa protein is uniquely regulated by protein phosphorylation. ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Induction of Apoptosis in Metastatic Breast Cancer Cells: XV. Downregulation of DNA Polymerase-α - Helicase Complex (Replisomes) and Glyco-Genes. Adv Exp Med Biol. 2018;1112:199-221 Authors: Basu SC, Boyle P, Ma R, Agarwal A, Basu M, Moskal JR, Banerjee S, Tuteja N Abstract In normal and cancer cells, successful cell division requires accurate duplication of chromosomal DNA. All cells require a multiprotein DNA duplication system (replisomes) for their existence. However, death of normal cells in our body occurs through the apoptotic process. During apoptotic process several crucial genes are dow...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Conclusion: In the Netherlands, the 21-RS test is applied both inside and outside the guideline-directed area. In case of discordance between the genomic and clinical risk, patients were treated in line with the result of the 21-RS.Public Health Genomics 2018;21:1 –8
Source: Public Health Genomics - Category: Genetics & Stem Cells Source Type: research
Conclusions: Circulating miRs and adiponectin were deregulated in postmenopausal women with BC.Gynecol Obstet Invest
Source: Gynecologic and Obstetric Investigation - Category: OBGYN Source Type: research
Long-time mammography screening critic Dr. Peter Gøtzsche plans to...Read more on AuntMinnie.comRelated Reading: Breast screening critics Gotzsche, Welch lose positions Breast screening skeptic Welch accused of plagiarism JAMA: Women need to be aware of mammography's harms ACR disputes NEJM paper on overdiagnosis Study questions value of early breast cancer detection
Source: Headlines - Category: Radiology Source Type: news
Condition:   Shared Decision Making Interventions:   Other: Intervention-specific Carevive questionnaire;   Other: Standard of Care questionnaire Sponsors:   University of Alabama at Birmingham;   American Cancer Society, Inc.;   Carevive Systems, Inc. Recruiting
Source: - Category: Research Source Type: clinical trials
Publication date: Available online 15 January 2019Source: Acta Pharmaceutica Sinica BAuthor(s): Liming Chen, Jose E. Manautou, Theodore P. Rasmussen, Xiao-bo ZhongAbstractPrecision medicine is a rapidly-developing modality of medicine in human healthcare. Based on each patient's unique characteristics, more accurate dosages and drug selection can be made to achieve better therapeutic efficacy and less adverse reactions in precision medicine. A patient's individual parameters that affect drug transporter action can be used to develop a precision medicine guidance, due to the fact that therapeutic efficacy and adverse reacti...
Source: Acta Pharmaceutica Sinica B - Category: Cancer & Oncology Source Type: research
Publication date: 15 January 2019Source: Cell Reports, Volume 26, Issue 3Author(s): Angela Santoro, Thalia Vlachou, Lucilla Luzi, Giorgio Melloni, Luca Mazzarella, Errico D’Elia, Xieraili Aobuli, Cristina Elisabetta Pasi, Linsey Reavie, Paola Bonetti, Simona Punzi, Lucia Casoli, Arianna Sabò, Maria Cristina Moroni, Gaetano Ivan Dellino, Bruno Amati, Francesco Nicassio, Luisa Lanfrancone, Pier Giuseppe PelicciSummaryLoss of p53 function is invariably associated with cancer. Its role in tumor growth was recently linked to its effects on cancer stem cells (CSCs), although the underlying molecular mechanisms remai...
Source: Cell Reports - Category: Cytology Source Type: research
Does the type and method of anesthesia administration used in breast cancer surgery impact recurrence-free survival?Anesthesiology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news
(Michigan Medicine - University of Michigan) A new study finds acupressure could be a low-cost, at-home solution to a suite of persistent side effects that linger after breast cancer treatment ends.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
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