NEAT1 contributes to breast cancer progression through modulating miR ‐448 and ZEB1

Journal of Cellular Physiology, EarlyView.
Source: Journal of Cellular Physiology - Category: Cytology Authors: Source Type: research

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Publication date: Available online 20 July 2018Source: Diagnostic and Interventional ImagingAuthor(s): P. Kong, L. Chen, X. Shi, H. Pan, M. Yu, H. Ge, J. Zhu, G. Ma, L. Li, Q. Ding, W. Zhou, S. WangAbstractPurposeTo evaluate the mechanism for enhancing cell death induced by microwave ablation (MWA) combined with doxorubicin treatment in breast cancer cells.Materials and methodsDifferent temperatures of heat treatment were used to mimic the tumor affected by sublethal heat during MWA in vitro. Breast cancer cells were treated at 43 °C and 45 °C, with or without doxorubicin. Cell viability, apoptosis, and i...
Source: Diagnostic and Interventional Imaging - Category: Radiology Source Type: research
Publication date: 10 November 2018Source: Sensors and Actuators B: Chemical, Volume 273Author(s): Yasaman Sadat Borghei, Morteza Hosseini, Mohammad Reza GanjaliAbstractMicroRNAs as regulators play an important role in gene expression and subsequently in various diseases. Newly, some studies show that up-regulation of miR-155 has been described in several types of human tumors. Due to the high importance of detecting miRNA with both fast speed and high sensitivity and the fundamental role of miR-155 in the breast cancer, we proposed a new miRNA detection method relying on photocatalytic activity of Cysteine capped gold nano...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
ConclusionsUltrasound evaluation may be the first level exam in case of suspicious symptomatic breast implant rupture. Importantly, our results demonstrate that magnetic resonance imaging could be avoided in all those cases where an extracapsular rupture has been diagnosed using ultrasound.Level of Evidence: Level IV, diagnostic study.
Source: European Journal of Plastic Surgery - Category: Cosmetic Surgery Source Type: research
ConclusionWithin an evolving context where services are centralised, new therapies emerge and subsequently come off patent, our understanding of the value of cancer therapies continues to evolve. This has important implications for the evaluation of new therapies and broader policy initiatives in this area.
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
AbstractBreast cancer is the most common cancer affecting women in South Africa. There is little knowledge of beliefs to help identify key areas to improve support and education in this demographically and culturally diverse population. Women with a variety of demographic and socioeconomic characteristics accessing care for breast cancer were asked their agreement to statements of knowledge and beliefs about breast cancer. Of the 259 participants, positive statements of medical cure (87.9%) and family support (90.5%) were most commonly believed. Beliefs in faith-based cure and alternative treatments were also present (79.5...
Source: Journal of Cancer Education - Category: Cancer & Oncology Source Type: research
AbstractThe aims of this study are to assess knowledge of inheritance characteristics of breast cancer and risk reduction strategies and to determine risk perception and the factors affecting risk perception of women with family history. There is a gap in our understanding of risk perception and knowledge of genetic aspect of breast cancer and risk reduction strategies in women with a family history of breast cancer. The study design is descriptive cross-sectional study. Between January 2015 and 2016 at a training and research hospital in Turkey, 117 women who were the first- and second-degree relatives of breast cancer pa...
Source: Journal of Cancer Education - Category: Cancer & Oncology Source Type: research
In this report, magnetic field enhancement of the photodynamic therapy (PDT) efficacy of a novel methoxypolyethyleneglycol-thiol-SPIONs-gold-meso-tetrakis(4-hydroxyphenyl)porphyrin conjugate (nano-drug) against MCF-7 breast cancer cells was evaluated. The nano-drug exhibited excellent blue and red emissions under suitable ultraviolet (380 nm) and visible (430 nm) excitations and was well taken up by the cells without any significant dark cytotoxicity after 24 h post-incubation. However, after exposure of cells to light for about 15 min, high rate of cell death was observed in a dose-dependent manner. In addition, t...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
In conclusion, HCT-B-DTX-PNPs were found to possess a higher affinity for breast cancer cells and induce a stronger cytotoxicity than that of other PNPs.Graphical abstract
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
CONCLUSIONS: Serum PSA could be a useful biomarker for the diagnosis of breast cancer, and a biomarker for the differential diagnosis of breast cancer from benign breast tumors. PMID: 30024607 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Publication date: Available online 15 September 2017Source: Inorganica Chimica ActaAuthor(s): Edward D. Cross, M. Trisha C. Ang, D. Douglas Richards, Amy C. Clemens, Harshiny Muthukumar, Robert McDonald, London Woodfolk, Karina Ckless, Matthias BierenstielAbstractNS-containing ligands with the 2-thioaniline motif and imine functional group linked phenyl, 2-pyridyl and 2-thienyl pendants were synthesized by imine condensation reactions with corresponding aldehydes. 2-(methylthio)-N-(2-thienylmethylene)-benzenamine is a new compound characterized by NMR, FTIR and UV–vis. Single crystal X-ray crystallographic data was o...
Source: Inorganica Chimica Acta - Category: Chemistry Source Type: research
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