Time-dependent changes in cardiorespiratory functions of anesthetized rats exposed to sustained hypoxia

Although cardiovascular responses may be altered by respiratory changes under prolonged hypoxia, the relationship between respiratory and cardiovascular changes remains unknown. The aim of the present study is to clarify cardiorespiratory changes in anesthetized rats during and after hypoxic conditions using simultaneous recordings of cardiorespiratory variables with 20-sec recording intervals. After air breathing for 20  min (pre-exposure period), rats were subjected to 10% O2 for 2 h (hypoxic exposure period) and then air for 30 min (recovery period).
Source: Autonomic Neuroscience: Basic and Clinical - Category: Neuroscience Authors: Source Type: research