Leptin Aggravates Reflux Esophagitis by Increasing Tissue Levels of Macrophage Migration Inhibitory Factor in Rats.

In conclusion, through enhancing the MIF-induced inflammatory signaling, leptin could contribute to the development of gastroesophageal reflux disease.
PMID: 29760351 [PubMed - in process]

Source: The Tohoku Journal of Experimental Medicine - May 17, 2018 Category: Research Authors: Murata T, Asanuma K, Ara N, Iijima K, Hatta W, Hamada S, Asano N, Koike T, Imatani A, Masamune A, Shimosegawa T Tags: Tohoku J Exp Med Source Type: research