Depression in men may lower chances for pregnancy, NIH study suggests

Women having trouble getting pregnant sometimes try yoga, meditation or mindfulness, and some research suggests that psychological stress may affect infertility. But what about men: Does their mental state affect a couple's ability to conceive? The latest research on this subject was published Thursday in the journal Fertility and Sterility and suggests that a link between mental health […]Related:CDC comes close to an all-clear on romaine lettuce as E. coli outbreak nears historic levelSurrogate mothers ask Supreme Court to stop ‘exploitation’ of women and babiesMore men with low-risk prostate cancer are forgoing aggressive treatment
Source: Washington Post: To Your Health - Category: Consumer Health News Source Type: news

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Publication date: Available online 25 May 2019Source: Preventive MedicineAuthor(s): Abbey E. Poirier, Yibing Ruan, Karena D. Volesky, Will D. King, Dylan E. O'Sullivan, Priyanka Gogna, Stephen D. Walter, Paul J. Villeneuve, Christine M. Friedenreich, Darren R. Brenner, ComPARe Study Team
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 20 May 2019Source: Annals of Physical and Rehabilitation MedicineAuthor(s): Alessandro de Sire, Marco Invernizzi, Lorenzo Lippi, Carlo Cisari, Levent Özçakar, Franco Franchignoni
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
Publication date: Available online 25 May 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Elisabeth Reiser, Stefanie Aust, Veronika Seebacher, Alexander Reinthaller, Hannah von Mersi, Richard Schwameis, Stephan Polterauer, Christoph Grimm, Samir Helmy-BaderAbstractObjectiveGamma-glutamyltransferase (GGT) is involved in tumor development, progression and chemotherapy resistance. The present study evaluated GGT serum levels as a preoperative predictive marker for ovarian cancer in patients with adnexal mass.Study DesignPreoperative GGT serum levels of 2235 patients with adnexal m...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Publication date: Available online 25 May 2019Source: Leukemia Research ReportsAuthor(s): Aya Nakaya, Shinya Fujita, Atsushi Satake, Takahisa Nakanishi, Yoshiko Azuma, Yukie Tsubokura, Ryo Saito, Akiko Konishi, Masaaki Hotta, Hideaki Yoshimura, Kazuyoshi Ishii, Tomoki Ito, Shosaku Nomura
Source: Leukemia Research Reports - Category: Hematology Source Type: research
ConclusionIn this study, no significant association was observed between visceral obesity and the number of metastatic lymph node, nor with survival at 5 and 10 years.ResumoIntroduçãoA presença de metastização ganglionar no câncer colorretal é determinante como fator de prognóstico e para planear o tratamento. A relação entre a presença de gordura visceral e o prognóstico não está totalmente documentada na literatura. Assim, pretende-se avaliar a existência de relação entre obesidade visceral e a presen&cced...
Source: Journal of Coloproctology - Category: Gastroenterology Source Type: research
Publication date: Available online 25 May 2019Source: Pharmacological ResearchAuthor(s): František Zálešák, David Jean-Yves Denis Bon, Jiří PospíšilAbstractLignans and neolignans are plant secondary metabolites derived from the oxidative coupling of phenylpropanoids. Biological activity of these phenolic compounds ranges from antioxidant, antitumor (terminaloside P, IC50 = 10 nM), anti-inflammatory, anti-neurodegenerative (schibitubin B, IC50 = 3.2 nM) and antiviral (patentiflorin A, IC50 = 14-23 nM) to antimicrobial. In addition, it was observed that several members of thi...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 25 May 2019Source: Journal of Pharmaceutical AnalysisAuthor(s): Jiawei Ye, Mingcheng Xu, Xueke Tian, Sheng Cai, Su ZengAbstractMicroRNAs (miRNAs) are a family of endogenous, small (approximately 22 nucleotides in length), noncoding, functional RNAs. With the development of molecular biology, the research of miRNA biological function has attracted significant interest, as abnormal miRNA expression is identified to contribute to serious human diseases such as cancers. Traditional methods for miRNA detection do not meet current demands. In particular, nanomaterial-based methods, nucleic acid...
Source: Journal of Pharmaceutical Analysis - Category: Drugs & Pharmacology Source Type: research
Conclusions: The results of the current study show that apoptosis is induced by the mitochondrial pathway accompanying with G2/M cycle arrest and inhibition of MAPK signaling cascades in human CCa HeLa cells, which can be used as a promising therapeutic drug for CCa.Graphical Abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 25 May 2019Source: Biochimica et Biophysica Acta (BBA) - Reviews on CancerAuthor(s): Maider Ibarrola-Villava, Andrés Cervantes, Alberto Bardelli
Source: Biochimica et Biophysica Acta (BBA) Reviews on Cancer - Category: Cancer & Oncology Source Type: research
In this study, we found that cofilin competes with tau for direct microtubule binding in vitro, in cells, and in vivo, which inhibits tau-induced microtubule assembly. Genetic reduction of cofilin mitigates tauopathy and synaptic defects in Tau-P301S mice and movement deficits in tau transgenic C. elegans. The pathogenic effects of cofilin are selectively mediated by activated cofilin, as active but not inactive cofilin selectively interacts with tubulin, destabilizes microtubules, and promotes tauopathy. These results therefore indicate that activated cofilin plays an essential intermediary role in neurotoxic signaling th...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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