Lab-confirmed prenatal exposure to Zika is linked to cardiac defects in infants

In this study, researchers performed echocardiograms in infants with laboratory confirmation of in utero exposure to Zika to investigate a potential link between prenatal Zika exposure and congenital heart defects.METHODThe researchers performed cardiac echocardiograms in infants born in Rio de Janeiro, Brazil, from November 2015 to January 2017. All infants were infected with the Zika virus during their mothers ’ pregnancy, as confirmed by laboratory tests.IMPACTWomen infected by Zika during pregnancy were 10 times more likely than the general population to give birth to infants with major cardiac defects. The researchers recommended that infants with suspected congenital Zika infection should be evaluated for cardiac problems. Because the heart defects noted in the study did not require immediate management, cardiac evaluation through physical examination and measure of oxygen saturation should be performed before discharge from the maternity hospital. If these are abnormal, evaluation by a pediatric cardiologist should be requested.  AUTHORSDr. Karin Nielsen-Saines of UCLA; Dr. Dulce Orofino, Dr. Carla Verona de Farias, Dr. Maria de Fatima Leite, Dr. Sheila Pone, Dr. Marcos Pone and Dr. Maria Elizabeth Moreira of the Fernandes Figueira Institute, Oswaldo Cruz Foundation; and Dr. Sonia Passos, Dr. Raquel de Oliveira, and Dr. Helena Teixeira Mendes of Evandro Chagas National Institute of Infectology at the Oswaldo Cruz Foundation.Orofino and Mendes are also associ...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news

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CONCLUSION: Hospitalization or death was not influenced by the type of RO, Al accumulation, or TMV classification. An elevated prevalence of osteoporosis and Al accumulation was detected. PMID: 31967202 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Conclusions. This study brings additional evidences of interest to investigate IgE, D-dimer serum/plasma levels and basophil blood counts in patients with CSU as they could be correlated to disease activity, response to treatment and/or autoimmunity. PMID: 31965967 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
DISCUSSION: The decline of positive test reactions to the fragrance mixes is mainly due to the reduced use of oakmoss containing atranol and chloroatranol, and HICC. Use of these substances in cosmetic products was prohibited within the EU starting in August 2019. Therefore, a further decline of the sensitization frequencies can be expected. A differentiated consideration of the individual fragrances under allergological aspects is urgently required. PMID: 31965209 [PubMed - as supplied by publisher]
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
Authors: Wagner N, Kamann S, Oppel E Abstract The design and development of insulin pumps and various glucose sensor systems has an enormous impact on life quality of diabetic patients. Surveillance and therapy of diabetes has improved due to the new diabetic devices, which are affixed to the patients' skin for several days. Since their introduction, irritant and allergic contact dermatitis have been frequently reported. Patients often acquire contact sensitization to isobornyl acrylate, N,N-dimethylacrylamide or formerly to 2‑ethyl-cyanoacrylate. These contact allergens were found in the patch, in the glue to af...
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
CONCLUSION: Although there is still a need for research, many parts of the contact allergy pathogenesis are now better understood. In particular, the essential role of the innate immune response not only for the sensitization but also for the elicitation phase seems to be established. Implementation of today's knowledge into new therapeutic approaches and their application testing remains important and exciting. PMID: 31965202 [PubMed - as supplied by publisher]
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
Publication date: February 2020Source: The Lancet Global Health, Volume 8, Issue 2Author(s): Louise Kuhn, Rakiya Saidu, Rosalind Boa, Ana Tergas, Jennifer Moodley, David Persing, Scott Campbell, Wei-Yann Tsai, Thomas C Wright, Lynette DennySummaryBackgroundHPV-based screen and treat is the recommended approach for cervical cancer screening in low-resource settings, but quite low specificity of human papillomavirus (HPV) testing, particularly in women living with HIV, leads to overtreatment. We evaluated whether HPV type restriction and more stringent cutoffs on Xpert HPV optimise performance characteristics of this assay f...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
In conclusion, our diagnostic prediction model uses easily obtainable information to identify children at increased risk of high blood pressure, offering an opportunity for targeted screening. This model enables to detect a higher proportion of children with high blood pressure than a strategy based on child overweight only.
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
OBJECTIVE: To investigate the adult mortality profile from eight causes of death in 10 Latin American countries (Argentina, Brazil, Chile, Colombia, Costa Rica, Ecuador, Mexico, Paraguay, Peru, and Uruguay) from 2000 to 2016. METHODS: The cause of ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
Authors: Yang L, Li M, Liu X, Wu M, Zhang J, Zhao L, Ding G, Yang X Abstract BACKGROUND: Remarkable achievements have been made for over two decades by implementing a universal salt iodization policy in China. However, changes in the standards and manufacturing of iodized salt have made it necessary to regularly monitor iodine intake and thyroid function in the population. Therefore, we aimed to evaluate iodine nutritional status using thyroid function and urinary iodine levels in pregnant women via a national survey. METHODS: Participants included pregnant women enrolled in the 2015 National Nutrition and Heal...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
This study accessed the patients information on demographic characteristics, physical signs and symptoms. Study population This is a cross-sectional and observational study carried out in Brazil during DENV and ZIKV epidemic occurred in 2016. Patients were assisted at the Healthy Unit UPA Coronel Antonino in Campo Grande, MS, Brazil from February to March of 2016. During the study 134 suspected arboviral infection cases were included and submitted to investigation. Patients presenting fever, rash during acute phase of infection (up to the 7th day after disease onset) followed by at least two of the following signals a...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
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